Share Email Print
cover

Proceedings Paper

Treatment planning platform for photodynamic therapy: architecture, function, and validation
Author(s): Brian C. Wilson; William Mark Whelan; Sean R. H. Davidson; Robert A. Weersink; Michael D. Sherar
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

The construction of a software platform for planning of photodynamic therapy (PDT) treatments is described. Its use is illustrated by the planning of a treatment of prostate cancer using multiple interstitial optical fiber sources. The effects of changing tissue optical properties, of photosensitizer photobleaching and of altering the power distribution between the sources are demonstrated. Validation tests of the PDT dose calculation algorithms and the software implementation of these are included. The possibility of compensating for misplaced sources is shown and confirmed experimentally in a tissue-simulating phantom. The future development of this platform and its integration into a complete solution planning-delivery-control platform is discussed.

Paper Details

Date Published: 6 June 2002
PDF: 8 pages
Proc. SPIE 4612, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XI, (6 June 2002); doi: 10.1117/12.469335
Show Author Affiliations
Brian C. Wilson, Univ. of Toronto, Ontario Cancer Institute/Princess Margaret Hospital, and Photonics Re (Canada)
William Mark Whelan, Univ. of Toronto and Ryerson Univ. (Canada)
Sean R. H. Davidson, Ontario Cancer Institute/Princess Margaret Hospital (Canada)
Robert A. Weersink, Photonics Research Ontario (Canada)
Michael D. Sherar, Univ. of Toronto and Ontario Cancer Institute/Princess Margaret Hospital (Canada)


Published in SPIE Proceedings Vol. 4612:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XI
Thomas J. Dougherty, Editor(s)

© SPIE. Terms of Use
Back to Top