Share Email Print
cover

Proceedings Paper

Neoplasm diagnostics based on fluorescence of polymethine dyes
Author(s): Michael Petrovitch Samtsov; Eugene S. Voropay; Vadim N. Chalov; Edvard A. Zhavrid
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Investigated polymethine dye TICS has near IR bands of fluorescence and absorption within the transparency region of biological tissues. It can be detected up to 1.5 cm from the surface of the skin. The intensity of a fluorescence signal of TICS is linear for doses up to 2 mg/kg in both tumor and muscle tissue. The ratio of an intensity of light induced fluorescence in tumor tissue to one in muscle tissue is up to 3.6 for rapidly growing tumors. The retention time of TICS is 7 days in all tissues. TICS can be used in the detection of tumor boundaries and tumor internal structure.

Paper Details

Date Published: 30 May 2002
PDF: 5 pages
Proc. SPIE 4749, ICONO 2001: Novel Trends in Nonlinear Laser Spectroscopy and Optical Diagnostics and Lasers in Chemistry, Biophysics, and Biomedicine, (30 May 2002); doi: 10.1117/12.468904
Show Author Affiliations
Michael Petrovitch Samtsov, A.N. Sevchenko Research Institute for Applied Physical Problems (Belarus)
Eugene S. Voropay, A.N. Sevchenko Research Institute for Applied Physical Problems (Belarus)
Vadim N. Chalov, N.N. Alexandrov Scientific Research Institute of Oncology and Medical Radiology (Belarus)
Edvard A. Zhavrid, N.N. Alexandrov Scientific Research Institute of Oncology and Medical Radiology (Belarus)


Published in SPIE Proceedings Vol. 4749:
ICONO 2001: Novel Trends in Nonlinear Laser Spectroscopy and Optical Diagnostics and Lasers in Chemistry, Biophysics, and Biomedicine

© SPIE. Terms of Use
Back to Top