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Proceedings Paper

Dual-detector polarimetry for compensation of motion artifact in a glucose sensing system
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Paper Abstract

Much work has been done to make the optical measurement of glucose concentrations in the aqueous humor a feasible, non- invasive, alternative for the blood finger stick, method currently used by people with diabetes mellitus. Recent work has demonstrated that the time lag between blood and aqueous humor glucose levels is within five minutes but there is still work to be done in overcoming the confounding effects of changing birefringence, due to motion artifact, on the detected glucose signal during in-vivo measurements. To address this issue, we designed and implemented a dual orthogonal polarization detection system. We present promising preliminary results that indicate that this method, with some slight modifications and optimization of our system, has the potential to extract glucose concentration information from a birefringent sample in the presence of motion artifact.

Paper Details

Date Published: 23 May 2002
PDF: 5 pages
Proc. SPIE 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II, (23 May 2002); doi: 10.1117/12.468329
Show Author Affiliations
Justin S. Baba, Texas A&M Univ. (United States)
Gerard L. Cote, Texas A&M Univ. (United States)


Published in SPIE Proceedings Vol. 4624:
Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II
Alexander V. Priezzhev; Gerard L. Cote, Editor(s)

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