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Proceedings Paper

Development imaging and experimental model for studying pathogenesis and treatment efficacy of postmastectomy lymphedema
Author(s): Ekateryna I. Galanzha; Valery V. Tuchin; Anastasiya V. Solov'eva; Tatyana V. Stepanova; Gregory E. Brill; Vladimir P. Zharov
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Paper Abstract

The experimental model was created during an abdominal dissection of the rat mesentery and ligation of the collecting vein of mesentery. It was found that mesentery edema was developed for 20-30 min. Simultaneously monitoring of main the parameters of blood and lymph flow revealed significant increasing of interstitial water amount (up to 3 times), reduction of blood microcirculation, increasing of blood vessels permeability, decreasing of lymph microvessels diameter, phasics contractions, and lymph flow velocity.

Paper Details

Date Published: 23 May 2002
PDF: 7 pages
Proc. SPIE 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II, (23 May 2002); doi: 10.1117/12.468315
Show Author Affiliations
Ekateryna I. Galanzha, Saratov State Univ. and Saratov State Medical Univ. (Russia)
Valery V. Tuchin, Saratov State Univ. (Russia)
Anastasiya V. Solov'eva, Saratov State Medical Univ. (Russia)
Tatyana V. Stepanova, Saratov State Medical Univ. (Russia)
Gregory E. Brill, Saratov State Medical Univ. (Russia)
Vladimir P. Zharov, Univ. of Arkansas for Medical Sciences (United States)


Published in SPIE Proceedings Vol. 4624:
Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II
Alexander V. Priezzhev; Gerard L. Cote, Editor(s)

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