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Proceedings Paper

EM-IntraSPECT algorithm with ordered subsets (OSEMIS) for nonuniform attenuation correction in cardiac imaging
Author(s): Andrzej Krol; Ifeanyi Echeruo; Roberto B. Solgado; Amol S. Hardikar; James E. Bowsher; David H. Feiglin; Frank Deaver Thomas; Edward Lipson; Ioana L. Coman
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Paper Abstract

Performance of the EM-IntraSPECT (EMIS) algorithm with ordered subsets (OSEMIS) for non-uniform attenuation correction in the chest was assessed. EMIS is a maximum- likelihood expectation maximization(MLEM) algorithm for simultaneously estimating SPECT emission and attenuation parameters from emission data alone. EMIS uses the activity within the patient as transmission tomography sources, with which attenuation coefficients can be estimated. However, the reconstruction time is long. The new algorithm, OSEMIS, is a modified EMIS algorithm based on ordered subsets. Emission Tc-99m SPECT data were acquired over 360 degree(s) in non-circular orbit from a physical chest phantom using clinical protocol. Both a normal and a defect heart were considered. OSEMIS was evaluated in comparison to EMIS and a conventional MLEM with a fixed uniform attenuation map. Wide ranges of image measures were evaluated, including noise, log-likelihood, and region quantification. Uniformity was assessed from bull's eye plots of the reconstructed images. For the appropriate subset size, OSEMIS yielded essentially the same images as EMIS and better than MLEM, but required only one-tenth as many iterations. Consequently, adequate images were available in about fifteen iterations.

Paper Details

Date Published: 9 May 2002
PDF: 6 pages
Proc. SPIE 4684, Medical Imaging 2002: Image Processing, (9 May 2002); doi: 10.1117/12.467057
Show Author Affiliations
Andrzej Krol, SUNY/Upstate Medical Univ. (United States)
Ifeanyi Echeruo, Syracuse Univ. (United States)
Roberto B. Solgado, SUNY/Upstate Medical Univ. and Syracuse Univ. (United States)
Amol S. Hardikar, Syracuse Univ. (United States)
James E. Bowsher, Duke Univ. Medical Ctr. (United States)
David H. Feiglin, SUNY/Upstate Medical Univ. (United States)
Frank Deaver Thomas, SUNY/Upstate Medical Univ. (United States)
Edward Lipson, Syracuse Univ. (United States)
Ioana L. Coman, Syracuse Univ. (United States)


Published in SPIE Proceedings Vol. 4684:
Medical Imaging 2002: Image Processing
Milan Sonka; J. Michael Fitzpatrick, Editor(s)

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