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Proceedings Paper

New generation of integrated probes for laser Doppler perfusion monitoring: construction and in-vivo results
Author(s): Alexander N. Serov; Sjoerd Oosterbaan; Janharm Nieland; Herma van Kranenburg; R. Verboom; Herman H. P. Th. Bekman; Frits F. M. de Mul; Wiendelt Steenbergen
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Paper Abstract

Integrated probes have been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device contains a VCSEL for illumination, and a chip with photodetectors, amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform. A Peltier element may be included for temperature stabilisation, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the probe designs are presented and some results of in vivo measurements are shown.

Paper Details

Date Published: 13 May 2002
PDF: 8 pages
Proc. SPIE 4615, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV, (13 May 2002); doi: 10.1117/12.466644
Show Author Affiliations
Alexander N. Serov, Univ. of Twente (Netherlands)
Sjoerd Oosterbaan, Univ. of Twente (Netherlands)
Janharm Nieland, Univ. of Twente (Netherlands)
Herma van Kranenburg, Univ. of Twente (Netherlands)
R. Verboom, TNO Physics and Electronics Lab. (Netherlands)
Herman H. P. Th. Bekman, TNO Physics and Electronics Lab. (Netherlands)
Frits F. M. de Mul, Univ. of Twente (Netherlands)
Wiendelt Steenbergen, Univ. of Twente (Netherlands)

Published in SPIE Proceedings Vol. 4615:
Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV
Tuan Vo-Dinh; David A. Benaron M.D.; Warren S. Grundfest M.D., Editor(s)

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