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Proceedings Paper

Selection of technique factors for contrast digital mammography
Author(s): Mia Skarpathiotakis; Stewart Bright; Martin Joel Yaffe; Fanny Jeunehomme; Serge L. Muller; James Gordon Mainprize
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Paper Abstract

Although screen-film mammography is the current standard for detecting abnormalities in the breast, the sensitivity can range from 40-95 percent. One of the reasons this occurs is because surrounding dense tissues obscure the visualization of cancers. To address this issue, we are investigating contrast digital mammography (CDM), which involves imaging the uptake of a non-ionic iodinated contrast agent with full-field digital mammography to detect and characterize masses in the breast. The technical aspects, including spectral optimization and image processing, for the implementation of CDM have been investigated and a clinical trial is being carried out to study the technique. This article describes an experimental study using an iodine detail phantom in combination with various breast equivalent plastics to evaluate technique parameters used when imaging patients. It is desirable to find the technique parameters that will maximize iodine contrast while delivering a reasonably low dose to the patient. It was found that the contrast can be increased up to 53 percent for thinner breasts by increasing the dose to a level that still remains lower than the dose that would be received by the breast from conventional screening images.

Paper Details

Date Published: 3 May 2002
PDF: 10 pages
Proc. SPIE 4682, Medical Imaging 2002: Physics of Medical Imaging, (3 May 2002); doi: 10.1117/12.465558
Show Author Affiliations
Mia Skarpathiotakis, Sunnybrook and Women's College Health Sciences Ctr. (Canada)
Stewart Bright, Sunnybrook and Women's College Health and Sciences Ctr. (Canada)
Martin Joel Yaffe, Sunnybrook and Women's College Health Sciences Ctr. (Canada)
Fanny Jeunehomme, GE Medical Systems (France)
Serge L. Muller, GE Medical Systems (France)
James Gordon Mainprize, Sunnybrook and Women's College Health Sciences Ctr. (Canada)

Published in SPIE Proceedings Vol. 4682:
Medical Imaging 2002: Physics of Medical Imaging
Larry E. Antonuk; Martin Joel Yaffe, Editor(s)

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