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Proceedings Paper

Application of laser speckle interferometry for monitoring the dynamics of lymph flow
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Paper Abstract

This paper applied the zero-crossings of laser speckle (ZCLS) method, utilizing the diffraction of a focused Gaussian beam, to obtain the dynamics of lymph flow on the rat mesentery in vivo. Two experiments were designed in this study: one was the intralipid model experiment; and the other was the lymph flow under the influence of isoprenaline. In the former, the temporal dynamics of intralipid flow were acquired indicating the validity of the ZCLS method. In the latter, the speckle interferometry results manifested no significant changes in the average velocities of lymph flow, which was consistent with the result obtained by the conventional physiological method of frame by frame analysis. However, the speckle results also manifested that the lymph flow dynamics changed under the drug's influence, which could not be gained by the conventional physiological methods. These indicated that the speckle interferometry technique was promising to determine lymph-flow diagnostics.

Paper Details

Date Published: 12 April 2002
PDF: 7 pages
Proc. SPIE 4536, International Workshop on Photonics and Imaging in Biology and Medicine, (12 April 2002); doi: 10.1117/12.462538
Show Author Affiliations
Haiying Cheng, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)
Zheng Wang, Huazhong Univ. of Science and Technology (China)
Lei Yao, Huazhong Univ. of Science and Technology (China)
Sergey S. Ulyanov, Saratov State Univ. (Russia)
Ekateryna I. Zakharova, Saratov Medical Univ. (Russia)
Shaoqun Zeng, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 4536:
International Workshop on Photonics and Imaging in Biology and Medicine

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