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Proceedings Paper

High-precision measurements in an optical tweezers for studying single-biomolecule motion
Author(s): H. T. Chen; Y. M. Li; L. R. Lou; H. W. Wang
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Paper Abstract

Based on the micron precision manipulation and measurement in the optical tweezers, we built an optical-trap system that can make quantitative measurement of displacement with nanometer resolution in millisecond time scale and then we can measure the piconewton force involved in the process. It is an eminent tool for manipulating biological specimens at the macromolecular level. In this paper we describe its technical properties, design, and make some discussion.

Paper Details

Date Published: 12 April 2002
PDF: 7 pages
Proc. SPIE 4536, International Workshop on Photonics and Imaging in Biology and Medicine, (12 April 2002); doi: 10.1117/12.462528
Show Author Affiliations
H. T. Chen, Univ. of Science and Technology of China (China)
Y. M. Li, Univ. of Science and Technology of China (China)
L. R. Lou, Univ. of Science and Technology of China (China)
H. W. Wang, Univ. of Science and Technology of China (China)


Published in SPIE Proceedings Vol. 4536:
International Workshop on Photonics and Imaging in Biology and Medicine
Qingming Luo; Britton Chance; Valery V. Tuchin, Editor(s)

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