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Proceedings Paper

Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation
Author(s): Glenn S. Edwards; M. Shane Hutson; Susanne Hauger
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Paper Abstract

We present in some detail a theoretical model that provides a dynamical account for the experimentally observed ablative properties of an FEL tuned near 6.45 microns. The model is based on thermal diffusion and chemical kinetics in a system of alternating layers of protein and saline as heated by an infrared Mark-III FEL. We compare exposure at 3.0 microns, where water is the sole absorber, to that at 6.45 microns, where both protein and water absorb. The picosecond pulses of the Mark-III superpulse are treated as a train of impulses. We consider the onset of both the helix-coil transition and chemical bond breaking in terms of the thermal, chemical, and mechanical properties of the system as well as laser wavelength and pulse structure.

Paper Details

Date Published: 1 April 2002
PDF: 10 pages
Proc. SPIE 4633, Commercial and Biomedical Applications of Ultrafast and Free-Electron Lasers, (1 April 2002); doi: 10.1117/12.461378
Show Author Affiliations
Glenn S. Edwards, Duke Univ. (United States)
M. Shane Hutson, Duke Univ. (United States)
Susanne Hauger, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 4633:
Commercial and Biomedical Applications of Ultrafast and Free-Electron Lasers
Joseph Neev; Glenn S. Edwards; Joseph Neev; Andreas Ostendorf; Andreas Ostendorf; John Clark Sutherland, Editor(s)

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