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Proceedings Paper

Computational intelligence for target assessment in Parkinson's disease
Author(s): Evangelia Micheli-Tzanakou; J. L. Hamilton; J. Zheng; Richard M. Lehman
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Paper Abstract

Recent advances in image and signal processing have created a new challenging environment for biomedical engineers. Methods that were developed for different fields are now finding a fertile ground in biomedicine, especially in the analysis of bio-signals and in the understanding of images. More and more, these methods are used in the operating room, helping surgeons, and in the physician's office as aids for diagnostic purposes. Neural Network (NN) research on the other hand, has gone a long way in the past decade. NNs now consist of many thousands of highly interconnected processing elements that can encode, store and recall relationships between different patterns by altering the weighting coefficients of inputs in a systematic way. Although they can generate reasonable outputs from unknown input patterns, and can tolerate a great deal of noise, they are very slow when run on a serial machine. We have used advanced signal processing and innovative image processing methods that are used along with computational intelligence for diagnostic purposes and as visualization aids inside and outside the operating room. Applications to be discussed include EEGs and field potentials in Parkinson's disease along with 3D reconstruction of MR or fMR brain images in Parkinson's patients, are currently used in the operating room for Pallidotomies and Deep Brain Stimulation (DBS).

Paper Details

Date Published: 14 November 2001
PDF: 16 pages
Proc. SPIE 4479, Applications and Science of Neural Networks, Fuzzy Systems, and Evolutionary Computation IV, (14 November 2001); doi: 10.1117/12.448327
Show Author Affiliations
Evangelia Micheli-Tzanakou, Rutgers Univ. and Robert Wood Johnson Univ. Hospital (United States)
J. L. Hamilton, Rutgers Univ. and Robert Wood Johnson Univ. Hospital (United States)
J. Zheng, Rutgers Univ. and Robert Wood Johnson Univ. Hospital (United States)
Richard M. Lehman, Rutgers Univ. and Robert Wood Johnson Univ. Hospital (United States)


Published in SPIE Proceedings Vol. 4479:
Applications and Science of Neural Networks, Fuzzy Systems, and Evolutionary Computation IV
Bruno Bosacchi; David B. Fogel; James C. Bezdek, Editor(s)

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