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Proceedings Paper

Monte Carlo investigation of separation of two absorbers in topographic image
Author(s): Takuma Kadoya; Eizo Moriwaki; Eiji Okada
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Paper Abstract

Near infrared topographic imaging is an effective instrument to image brain-cortex activity. The image is reconstructed by changes in light intensity detected with multi-channel source-detector pairs. However, light scattering in tissue prevents us from improving the spatial resolution of the reconstructed image, hence it is important to evaluate the effect of scattering on the spatial resolution of the reconstructed image. In this study, separation of two absorbers in topographic image is investigated by Monte Carlo simulation to evaluate the spatial resolution of topographic imaging. Because of heterogeneity of tissue, especially presence of low scattering CSF layer affects the light propagation in the adult brain. The adult head model consists of three layers including a low scattering medium. In case where the separation of two absorbers is greater than the distance between adjacent measurment points, the two absorbers can be separated in the topographic image.

Paper Details

Date Published: 2 November 2001
PDF: 8 pages
Proc. SPIE 4431, Photon Migration, Optical Coherence Tomography, and Microscopy, (2 November 2001); doi: 10.1117/12.447418
Show Author Affiliations
Takuma Kadoya, Keio Univ. (Japan)
Eizo Moriwaki, Keio Univ. (Japan)
Eiji Okada, Keio Univ. (Japan)


Published in SPIE Proceedings Vol. 4431:
Photon Migration, Optical Coherence Tomography, and Microscopy
Stefan Andersson-Engels; Michael F. Kaschke, Editor(s)

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