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Proceedings Paper

Approach to sequence DNA without tagging
Author(s): Sanjun Niu; Ravi F. Saraf
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Paper Abstract

A concept to sequence DNA without tagging the molecule is developed. The fabrication process is compatible with current microelectronics and (emerging) soft-material fabrication technologies, allowing the method to be integrable with MEMS and lab-on-a-chip devices. The preliminary results indicate sensitivity in the nano-gram regime for 100 micron-square pixels. The technology can be extended to perform combinatorial analysis with on-line measurement in real-time during the hybridization process.

Paper Details

Date Published: 23 October 2001
PDF: 9 pages
Proc. SPIE 4512, Complex Adaptive Structures, (23 October 2001); doi: 10.1117/12.446773
Show Author Affiliations
Sanjun Niu, Virginia Polytechnic Institute and State Univ. (United States)
Ravi F. Saraf, Virginia Polytechnic Institute and State Univ. (United States)

Published in SPIE Proceedings Vol. 4512:
Complex Adaptive Structures
William B. Spillman, Editor(s)

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