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Proceedings Paper

Interferometric detection of laser-induced microbubbles in the retinal pigment epithelium
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Paper Abstract

We developed an interferometric technique in order to detect microbubble formation within porcine retinal pigment epithelial (RPE) cells ex vivo after short pulsed laser exposure (527nm, 350ns). The irradiated surface of the RPE tissue samples was monitored by a Michelson interferometer. The obtained interferometric transients revealed bubble dynamics and were compared to optoacoustic transients recorded simultaneously. This interferometric technique might be useful for in vivo dosimetry during selective RPE-treatment.

Paper Details

Date Published: 26 October 2001
PDF: 6 pages
Proc. SPIE 4433, Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy, (26 October 2001); doi: 10.1117/12.446505
Show Author Affiliations
Joerg Neumann, Medical Laser Ctr. Luebeck GmbH (Germany)
Ralf Brinkmann, Medical Laser Ctr. Luebeck GmbH (Germany)


Published in SPIE Proceedings Vol. 4433:
Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy
Reginald Birngruber; Hubert van den Bergh, Editor(s)

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