Share Email Print

Proceedings Paper

Novel bonding method for polymer-based microfluidic platforms
Author(s): Siyi Lai; Yeny Hudiono; Ly James Lee; Sylvia Daunert; Marc J. Madou
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Polymer-based microfluidic platforms have great potential for use in BioMEMS applications because many polymers are low cost, biocompatible, and have good processibility. However, packaging (i.e., sealing the platform with a lid) is a challenging issue in their fabrication. In this paper, we compare several available bonding techniques such as adhesive tape bonding and chemical-assisted bonding with a new method recently developed in our lab: resin-gas injection-assisted bonding. This new approach can easily seal microfluidic devices with micron and sub-micron sized channels without blocking the flow path. It can also be used to modify the channel shape, size, and surface characteristics (e.g., hydrophilicity, degree of protein adsorption). By applying the masking technique, local modification of the channel surface can be achieved through cascade resin-gas injection. Experiments are carried out to demonstrate the bonding efficiency and surface modification.

Paper Details

Date Published: 28 September 2001
PDF: 8 pages
Proc. SPIE 4557, Micromachining and Microfabrication Process Technology VII, (28 September 2001); doi: 10.1117/12.442956
Show Author Affiliations
Siyi Lai, The Ohio State Univ. (United States)
Yeny Hudiono, The Ohio State Univ. (United States)
Ly James Lee, The Ohio State Univ. (United States)
Sylvia Daunert, Univ. of Kentucky (United States)
Marc J. Madou, Nanogen, Inc. (United States)

Published in SPIE Proceedings Vol. 4557:
Micromachining and Microfabrication Process Technology VII
Jean Michel Karam; John A. Yasaitis, Editor(s)

© SPIE. Terms of Use
Back to Top