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Proceedings Paper

Near-infrared optical monitoring of cardiac oxygen sufficiency through thoracic wall without open-chest surgery
Author(s): Yasuyuki Kakihana; Mamoru Tamura
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Paper Abstract

The cardiac function is exquisitely sensitive to oxygen, because its energy production mainly depends on the oxidative phosphorylation at mitochondria. Thus, oxygenation state of the tissue is critical. Cytochrome a,a3, hemoglobin and myoglobin, which play indispensable role in the oxygen metabolism, have the broad absorption band in near infrared (NIR) region and the light in this region easily penetrates biological tissues. Using NIR spectrophotometry, we attempted to measure the redox state of the copper in cytochrome a,a3 in rat heart through thoracic wall without open chest. The result is given in this paper.

Paper Details

Date Published: 1 May 1991
PDF: 8 pages
Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); doi: 10.1117/12.44202
Show Author Affiliations
Yasuyuki Kakihana, Hokkaido Univ. (Japan)
Mamoru Tamura, Hokkaido Univ. (Japan)

Published in SPIE Proceedings Vol. 1431:
Time-Resolved Spectroscopy and Imaging of Tissues
Britton Chance, Editor(s)

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