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Proceedings Paper

Time-resolved diffuse reflectance and transmittance studies in tissue simulating phantoms: a comparison between theory and experiment
Author(s): Sten Madsen; Michael S. Patterson; Brian C. Wilson; Young D. Park; John David Moulton; Steven L. Jacques; Yaron Hefetz
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Paper Abstract

When a picosecond light pulse is incident on an optically turbid medium such as tissue, the temporal distribution of diffusely reflected and transmitted photons depends on the optical absorption and scattering properties of the medium. From diffusion theory it is possible to derive analytic expressions for the pulse shape in terms of the optical interaction coefficients of a homogeneous semi-infinite medium. Experimental tests of this model in tissue-simulating liquid phantoms of different geometries are presented here.

Paper Details

Date Published: 1 May 1991
PDF: 10 pages
Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); doi: 10.1117/12.44176
Show Author Affiliations
Sten Madsen, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
Michael S. Patterson, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
Brian C. Wilson, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
Young D. Park, Massachusetts Institute of Technology (United States)
John David Moulton, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
Steven L. Jacques, Univ. of Texas M.D. Anderson Hospital (United States)
Yaron Hefetz, Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 1431:
Time-Resolved Spectroscopy and Imaging of Tissues
Britton Chance, Editor(s)

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