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Proceedings Paper

Quantitative analysis at the molecular level of laser/neural tissue interactions using a liposome model system
Author(s): David L. VanderMeulen; Prabhakar Misra; Jason Michael; Kenneth G. Spears; Mustafa Khoka
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Paper Abstract

The research has focused on understanding the effects of irradiating liposomes containing organic dyes with nanosecond and picosecond pulses at 532 nm from Nd:YAG lasers. Time-correlated photon counting and phase-resolved fluorescence spectroscopy techniques have been employed to obtain multicomponent fluorescence lifetimes for the dye-liposome system. A quantitative model based on the experimental data supports a photo-induced thermal mechanism for release of liposome contents.

Paper Details

Date Published: 1 May 1991
PDF: 8 pages
Proc. SPIE 1428, Three-Dimensional Bioimaging Systems and Lasers in the Neurosciences, (1 May 1991); doi: 10.1117/12.44149
Show Author Affiliations
David L. VanderMeulen, Chicago Institute for NeuroSurgery and NeuroResearch (United States)
Prabhakar Misra, Howard Univ. (United States)
Jason Michael, Howard Univ. (United States)
Kenneth G. Spears, Northwestern Univ. (United States)
Mustafa Khoka, Northwestern Univ. (United States)


Published in SPIE Proceedings Vol. 1428:
Three-Dimensional Bioimaging Systems and Lasers in the Neurosciences
James E. Boggan; Leonard J. Cerullo; Louis C. Smith, Editor(s)

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