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Proceedings Paper

Photosensitized receptor inactivation with He-Ne laser: preliminary results
Author(s): Simon Arber; William Zev Rymer; David Crumrine
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Paper Abstract

Receptor inactivation by means of chromophore-conjugated receptor ligands and laser is discussed. The results of preliminary experiments aimed at inactivation of FMRFamide receptors in snail neurons using a He-Ne laser and FMRFamide analogs conjugated with Azure B are presented. Because the conjugates synthesized apparently bound to another class of binding sites on the neuronal membrane, the FMRFamide receptor inactivation was not achieved. However, laser inactivation was demonstrated for the conjugate binding sites.

Paper Details

Date Published: 1 May 1991
PDF: 7 pages
Proc. SPIE 1428, Three-Dimensional Bioimaging Systems and Lasers in the Neurosciences, (1 May 1991); doi: 10.1117/12.44132
Show Author Affiliations
Simon Arber, Chicago Institute for Neurosurgery and Neuroresearch (United States)
William Zev Rymer, Chicago Institute for Neurosurgery and Neuroresearch (United States)
David Crumrine, Loyola Univ. (United States)


Published in SPIE Proceedings Vol. 1428:
Three-Dimensional Bioimaging Systems and Lasers in the Neurosciences
James E. Boggan; Leonard J. Cerullo; Louis C. Smith, Editor(s)

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