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Proceedings Paper

Tissue interactions of ball-tipped and multifiber catheters
Author(s): David C. Mitchell; Roy E. Smith; Tena K. Walters; Alan Murray; Richard F. M. Wood
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Paper Abstract

Ablation of atheromatous plaques and normal aortic wall was undertaken using ball-tipped fibers, 9Fr and 7Fr multifiber catheters coupled to a pulsed dye laser (Model MDL-1P, Candela Laser Corp., Wayland MA operating at a wavelength of 504 nm. The delivery devices were placed in contact with, and perpendicular to, the endothelial surface of fresh aortic specimens. Catheters were weighted to produce identical pressures on the tissue (230 kPa). The depth and diameters of the craters were measured by microscopy to allow calculation of the volume of tissue removed. Laser energy produced craters in areas of normal aortic wall and in both fibrous and yellow plaque. For given energy levels the largest craters were formed in soft yellow plaque. A significantly smaller volume of tissue was ablated in fibrous plaques with the shallowest lesions in normal vessel wall. The most efficient ablation of fibrous plaque was obtained using the 7Fr multifiber catheter. Soft yellow plaque was encountered relatively infrequently in the specimens examined. These lesions were ablated more readily by the ball-tipped device than the multifiber catheters. Shattering of calcified plaque was produced at 100 mJ/pulse with the ball-tip and at 125 mJ/p with the multifiber catheters. Crater formation in calcified plaque was very variable and highly dependent on plaque color.

Paper Details

Date Published: 1 June 1991
PDF: 8 pages
Proc. SPIE 1427, Laser-Tissue Interaction II, (1 June 1991); doi: 10.1117/12.44102
Show Author Affiliations
David C. Mitchell, St. Bartholomew's Hospital (United Kingdom)
Roy E. Smith, St. Bartholomew's Hospital (United Kingdom)
Tena K. Walters, St. Bartholomew's Hospital (United Kingdom)
Alan Murray, St. Bartholomew's Hospital (United Kingdom)
Richard F. M. Wood, St. Bartholomew's Hospital (United Kingdom)

Published in SPIE Proceedings Vol. 1427:
Laser-Tissue Interaction II
Steven L. Jacques, Editor(s)

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