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Proceedings Paper

Photodynamic therapy in the prophylactic management of bladder cancer
Author(s): Unyime O. Nseyo; Scott L. Lundahl; Daniel C. Merrill
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Paper Abstract

Nine patients were treated with red light whole bladder photodynamic therapy (WBPDT): five had mucosal involvement (Ta) and four submucosal invasion (T1). Patients received slow intravenous injection with 2mg/kg body weight of photofrin 48-72 hours before undergoing global light treatment via a 22-French cystoscope with a 400-micron quartz fiber bulb (isotropic) tip fiber. Three months after PDT, eight of the patients had normal cystoscopy, and negative biopsy and urine cytology. Two patients who had recurrences at six and twelve months were retreated with a higher dose (20 J/cm2). They had no increased morbidity and no evidence of recurrent disease six months later. WBPDT should be considered as an important alternative treatment for patients who have recurrent or refractory superficial bladder cancer.

Paper Details

Date Published: 1 June 1991
PDF: 6 pages
Proc. SPIE 1426, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, (1 June 1991); doi: 10.1117/12.44068
Show Author Affiliations
Unyime O. Nseyo, Univ. of California/Davis and Veterans Administration Medica (United States)
Scott L. Lundahl, Univ. of California/Davis and Veterans Administration Medica (United States)
Daniel C. Merrill, Univ. of California/Davis and Veterans Administration Medica (United States)


Published in SPIE Proceedings Vol. 1426:
Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques
Thomas J. Dougherty, Editor(s)

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