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Proceedings Paper

Evaluation of Nile Blue E chalcogen analogs as PDT agents
Author(s): James W. Foley; Louis Cincotta; Anthony H. Cincotta
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Paper Abstract

The photodynamic therapeutic properties of the oxygen containing benzophenoxazine dye Nile Blue E, NBEO, and its sulfur and selenium analogs, NBES and NBESe, were evaluated in cell culture using a murine mammary sarcoma (EMT-6) cell line. The photosensitizing efficacies of the dyes were found to correlate with their ability to generate singlet oxygen and to increase in the order: NBEO

Paper Details

Date Published: 1 June 1991
PDF: 8 pages
Proc. SPIE 1426, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, (1 June 1991); doi: 10.1117/12.44060
Show Author Affiliations
James W. Foley, Rowland Institute for Science (United States)
Louis Cincotta, Rowland Institute for Science (United States)
Anthony H. Cincotta, Massachusetts General Hospital, Harvard Medical School, and (United States)


Published in SPIE Proceedings Vol. 1426:
Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques
Thomas J. Dougherty, Editor(s)

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