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Proceedings Paper

Restenosis after hot-tip laser-balloon angioplasty: histologic evaluation of the samples removed by Simpson atherectomy
Author(s): Enrico Barbieri; Pietro Tanganelli; Giuseppe Taddei; Antonio Perbellini; Vito Attino; Gianni Destro; Piero Zardini
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Paper Abstract

Laser balloon angioplasty has been used in recent years to treat peripheral artery disease. Despite a primary success the technique is plagued by a high restenosis rate. Directional atherectomy was performed in a small group of patients affected by primitive stenosis or restenosis after an invasive procedure. Light microscopy, immunohistochemistry, and transmission electron microscopy have identified the cellular component of intimal hyperplasia as smooth muscle cells in an active synthetic phenotype. The arterial healing process after invasive procedures seems to develop similarly independently of the device employed.

Paper Details

Date Published: 1 May 1991
PDF: 6 pages
Proc. SPIE 1425, Diagnostic and Therapeutic Cardiovascular Interventions, (1 May 1991); doi: 10.1117/12.44024
Show Author Affiliations
Enrico Barbieri, Univ. of Verona (Italy)
Pietro Tanganelli, Univ. of Verona and Univ. of Siena (Italy)
Giuseppe Taddei, Univ. of Verona (Italy)
Antonio Perbellini, Univ. of Verona (Italy)
Vito Attino, Univ. of Verona and Univ. of Siena (Italy)
Gianni Destro, Univ. of Verona (Italy)
Piero Zardini, Univ. of Verona (Italy)


Published in SPIE Proceedings Vol. 1425:
Diagnostic and Therapeutic Cardiovascular Interventions
George S. Abela, Editor(s)

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