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Proceedings Paper

Electron microscopic study on black pig skin irradiated with pulsed dye laser (504 nm)
Author(s): Yukio Yasuda; Oon Tian Tan; Amal K. Kurban; Sadao Tsukada
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Paper Abstract

Selective damage of epidermal pigment cells induced by 504 nm pulsed dye laser at different pulse durations and fluence on black pig skin was examined electron microscopically. Epidermal melanosomes were satisfactorily disrupted at shorter pulse duration (100 ns). Epidermal blister formation and necrosis were seen at 2 days postirradiation, and reepithelization was evident at 7 days postirradiation in all specimens. Repigmentation was evident 21 to 56 days after irradiation. Histological pigmentary incontinence was evident at 2 days and persisted until 56 days postirradiation. This phenomenon was observed more frequently in skin exposed to longer pulse duration and at low fluences. Optimal parameters required to induce epidermal melanosome disruption using the 504 nm pulsed dye laser will be discussed.

Paper Details

Date Published: 1 June 1991
PDF: 6 pages
Proc. SPIE 1422, Lasers in Dermatology and Tissue Welding, (1 June 1991); doi: 10.1117/12.43940
Show Author Affiliations
Yukio Yasuda, Kanazawa Medical Univ. (Japan)
Oon Tian Tan, Boston City Hospital (United States)
Amal K. Kurban, Boston Univ. Medical Ctr. (United States)
Sadao Tsukada, Kanazawa Medical Univ. (Japan)

Published in SPIE Proceedings Vol. 1422:
Lasers in Dermatology and Tissue Welding
Oon Tian Tan; Rodney A. White; John V. White, Editor(s)

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