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Proceedings Paper

Preliminary results with sutured colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser
Author(s): Steven K. Libutti; Matthew R. Williams; Mehmet Cengiz Oz; Kenneth A. Forde; Lawrence S. Bass; Samuel Weinstein; Joseph S. Auteri; Michael R. Treat; Roman Nowygrod
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Paper Abstract

A common cause of morbidity in patients recovering from bowel surgery is leakage from colonic anastomoses. A technique utilizing a laser activated protein solder to strengthen colonic anastomoses in a canine model was evaluated. Following creation of six single-layer interrupted suture anastomoses in four dogs, a protein solder consisting of indocyanine green dye and fibrinogen was topically appied to the serosal surface and exposed to 808 nm continuous wave diode laser energy. Immediately following anastomosis, the mean leakage pressure of sutures alone was 129 +/- 14 mm hg (n equals 6), while the mean leakage pressure of sutures reinforced with the laser welded solder was 312 +/- 32 mm hg (n equals 6) (p <0.001). Histologic examination of sections take through the anastomosis demonstrated a layer of fibrinogen across the anastomotic gap without evidence of thermal injury. Laser activated protein solder significantly enhances the immediate strength of sutured colonic anastomoses without causing appreciable thermal injury to surrounding tissues.

Paper Details

Date Published: 1 July 1991
PDF: 4 pages
Proc. SPIE 1421, Lasers in Urology, Laparoscopy, and General Surgery, (1 July 1991); doi: 10.1117/12.43926
Show Author Affiliations
Steven K. Libutti, Columbia Univ. College of Physicians and Surgeons (United States)
Matthew R. Williams, Columbia Univ. College of Physicians and Surgeons (United States)
Mehmet Cengiz Oz, Columbia Univ. College of Physicians and Surgeons (United States)
Kenneth A. Forde, Columbia Univ. College of Physicians and Surgeons (United States)
Lawrence S. Bass, Columbia Univ. College of Physicians and Surgeons (United States)
Samuel Weinstein, Columbia Univ. College of Physicians and Surgeons (United States)
Joseph S. Auteri, Columbia Univ. College of Physicians and Surgeons (United States)
Michael R. Treat, Columbia Univ. College of Physicians and Surgeons (United States)
Roman Nowygrod, Columbia Univ. College of Physicians and Surgeons (United States)


Published in SPIE Proceedings Vol. 1421:
Lasers in Urology, Laparoscopy, and General Surgery
Graham M. Watson; Rudolf W. Steiner; Joseph J. Pietrafitta, Editor(s)

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