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Proceedings Paper

Sampling volume produced by shallow optical probes in skin reflectance measurements
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Paper Abstract

The absolute quantified measurement of hemoglobin skin blood saturation from collected reflectance spectra of the skin is complicated by the fact that the blood content of tissues can vary both in the spatial distribution and in the amount. These measurements require an understanding of which vascular bed is primarily responsible for the detected signal. Knowing the spatial detector depth sensitivity makes it possible to find the best range of different probe geometries for the measurements of signal from the required zones and group of vessels inside the skin. To facilitate this we have developed a Monte Carlo simulation to estimate the sampling volume offered by fiber-optic probes with a small source detector spacing, and by the confocal probe. The optical properties of the modeled medium were taken to be optical properties of the Caucasian type of skin tissues in the visible range of the spectrum. The authors propose this simple numerical methods as a tool for the probes examination to yield measurements which are preferentially sensitive to blood at different depths within the skin.

Paper Details

Date Published: 22 August 2001
PDF: 9 pages
Proc. SPIE 4427, Imaging of Tissue Structure and Function, (22 August 2001); doi: 10.1117/12.438426
Show Author Affiliations
Igor Victorovich Meglinski, Univ. of Exeter (United Kingdom)
Stephen John Matcher, Univ. of Exeter (United Kingdom)

Published in SPIE Proceedings Vol. 4427:
Imaging of Tissue Structure and Function
Valery V. Tuchin; Qingming Luo; Sergey S. Ulyanov, Editor(s)

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