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Proceedings Paper

Effects of IR wavelength on ablation mechanics: a study of acoustic signals
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Paper Abstract

The effects of wavelength on infrared (IR) laser ablation with a free electron laser were studied by analyzing the acoustic signals produced during ablation of gelatin and tissue samples. The acoustic signals resulting from surface ablation of the samples were recorded with a piezoelectric microphone and the acoustic energy contained in the signal was calculated for samples of varying mechanical strength. Gelatin samples of different mechanical strengths were made by varying the water concentration in the gels to 70% and 90% wt./vol. The gels were irradiated at wavelengths of λ = 2.94, 2.80, and 6.45 μm with the measured acoustic energy normalized to the incident laser pulse energy. The results showed that while there was a statistically significant difference in the average acoustic energy measured for both concentrations of gelatin at λ = 2.94 and 2.80 μm, there was no difference in the average acoustic energy for the two concentrations of gelatin at λ = 6.45 micrometers . This supports the model of mechanical weakening of the sample by breaking the amide II molecular bonds in proteins, originally proposed by Edwards et al.

Paper Details

Date Published: 9 July 2001
PDF: 6 pages
Proc. SPIE 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, (9 July 2001); doi: 10.1117/12.434702
Show Author Affiliations
Stephen R. Uhlhorn, Vanderbilt Univ. (United States)
David Mongin, Vanderbilt Univ. (United States)
Mark A. Mackanos, Vanderbilt Univ. (United States)
E. Duco Jansen, Vanderbilt Univ. (United States)


Published in SPIE Proceedings Vol. 4257:
Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical
Donald Dean Duncan; Peter C. Johnson; Donald Dean Duncan; Steven L. Jacques; Peter C. Johnson, Editor(s)

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