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Proceedings Paper

Mueller-matrix description of collimated light transmission through liver, muscle, and skin
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Paper Abstract

Propagation of polarized light through liver, muscle and skin was studied using the Mueller Matrix formalism. Collimated HeNe laser light was passed through a set of polarization elements to create one of four possible polarization states (horizontal (H), vertical (V) and 45- degree (P) orientations of linearly polarized light, and right circularly (R) polarized light). The beam passed through thin sections of tissue of varying thickness (0.2- 0.9 mm thick). The unscattered, collimated, transmitted light passed through a second set of polarization elements to analyze for transmission of each of the 4 possible polarization states (H,V,P,R). Transmitted intensities for 16 possible combinations of source and detector polarization yielded a data matrix that was converted into a Mueller matrix describing the propagation properties of the tissue. The results were roughly consistent with all three tissue types behaving as ideal retarders whose birefringent values, dn = (Delta) *wavelength/(2*(pi) *thickness), were in the range of 1x10-3 to 5x10-3 which is consistent with the literature. The order of the strength of birefringence was liver < muscle < skin. Although the above birefringence values may apply to muscle, the structure of liver and skin are not necessarily consistent with the ideal retarder model and further work is needed.

Paper Details

Date Published: 9 July 2001
PDF: 7 pages
Proc. SPIE 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, (9 July 2001); doi: 10.1117/12.434693
Show Author Affiliations
Jessica C. Ramella-Roman, Oregon Medical Laser Ctr./Providence St. Vincent Medical Ctr., Oregon Graduate Institute o (United States)
Steven L. Jacques, Oregon Medical Laser Ctr./Providence St. Vincent Medical Ctr., Oregon Graduate Institute o (United States)


Published in SPIE Proceedings Vol. 4257:
Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical
Donald Dean Duncan; Peter C. Johnson; Donald Dean Duncan; Steven L. Jacques; Peter C. Johnson, Editor(s)

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