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Proceedings Paper

Interpreting Mueller matrix images of tissues
Author(s): Matthew H. Smith
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Paper Abstract

In recent years, several investigators have begun to explore polarized light imagery as a potential diagnostic tool. For example, polarimetric images have shown promise in identifying a variety of dermatological conditions. Because tissues tend to depolarize a large fraction (~85%) of incident light, the Mueller calculus lends itself well to these applications. A particular property of the Mueller matrix, the Depolarization Index, has demonstrated promise in discriminating between cancerous and benign moles. In this paper, we discuss the depolarizing aspects of tissues, however we primarily attempt to analyze the small fraction of light that has retained a polarization state. Analyzing the residual polarizing properties of a sample is challenging, and it requires a polar decomposition of the measured Mueller matrix into the basic properties of diattenuation, retardance, and depolarization. The diattenuation and retardance images contain information about the complex refractive index of the tissue, including any spatial variations in the index. We present measurements of the diattenuation and retardance of laser light reflected from skin as a function if incident angle and scattered angle.

Paper Details

Date Published: 9 July 2001
PDF: 8 pages
Proc. SPIE 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, (9 July 2001); doi: 10.1117/12.434690
Show Author Affiliations
Matthew H. Smith, Univ. of Alabama in Huntsville (United States)

Published in SPIE Proceedings Vol. 4257:
Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical
Donald Dean Duncan; Donald Dean Duncan; Steven L. Jacques; Peter C. Johnson; Peter C. Johnson, Editor(s)

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