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Proceedings Paper

Noninvasive brain function measurement system: optical topography
Author(s): Tsuyoshi Yamamoto; Atsushi Maki; Yuichi Yamashita; Yukari Tanikawa; Yukio Yamada; Hideaki Koizumi
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Paper Abstract

Authors proposed optical topography to visualize the blood- volume change in the cortex associated with brain activation. The diffusion equation was used to obtain the sensitivity distribution of the blood-volume change. We show that the sensitivity distribution agrees with that obtained by the Monte-Carlo simulation. We then developed a phantom that simulates the light scattering property and brain activation in the cortex. Topographic images of the absorber in the phantom are obtained, and high location accuracy but spatial resolution of the topographic image were found. In addition, we derived a methodology to arrange optodes at high density in order to improve the spatial resolution of the topographic image.

Paper Details

Date Published: 29 June 2001
PDF: 12 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434512
Show Author Affiliations
Tsuyoshi Yamamoto, Hitachi, Ltd. (Japan)
Atsushi Maki, Hitachi, Ltd. (Japan)
Yuichi Yamashita, Hitachi, Ltd. (Japan)
Yukari Tanikawa, Mechanical Engineering Lab. (Japan)
Yukio Yamada, Mechanical Engineering Lab. (Japan)
Hideaki Koizumi, Hitachi, Ltd. (Japan)

Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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