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Proceedings Paper

Imaging of spatio-temporal coincident states by dynamic optical tomography
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Paper Abstract

The utility of optical tomography as a static imaging modality is limited by its intrinsically low spatial resolution and quantitative accuracy. When applied to dynamic measurements, however, optical imaging methods have the potential to assess tissue function as revealed by temporal variations in tissue optical properties. These variations are a consequence of vascular hemodynamic processes, which are known to exhibit considerably spatiotemporal heterogeneity. In this report we provide evidence, from simulation, that complex dynamic behavior in optical coefficients occurring in localized regions in highly scattering media can be accurately characterized by the method of dynamic optical tomography, even in the limiting case of spatiotemporally coincident behavior.

Paper Details

Date Published: 29 June 2001
PDF: 11 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434487
Show Author Affiliations
Harry L. Graber, SUNY/Downstate Medical Ctr. (United States)
Yaling Pei, NIRx Medical Technologies Corp. (United States)
Randall Locke Barbour, SUNY/Downstate Medical Ctr. (USA) and NIRx Medical Technologies Corp. (United States)

Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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