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Proceedings Paper

Normalized-constraint method for minimizing interparameter cross-talk in reconstructed images of spatially heterogeneous scattering and absorption coefficients
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Paper Abstract

In this report, we present a method to reduce the cross-talk problem in optical tomography. The method described is an extension of a previously reported perturbation formulation related to relative detector values, and employs a weight matrix scaling technique together with a constrained CGD method for imaging reconstruction. Results from numerical and experimental studies using DC measurement data demonstrate that the approach can effectively isolate absorption and scattering heterogeneities, even for complex combinations of perturbations in optical properties. The derive method is remarkably stable to errors originating from an insufficiently accurate estimate of properties of the reference medium.

Paper Details

Date Published: 29 June 2001
PDF: 9 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434481
Show Author Affiliations
Yaling Pei, NIRx Medical Technologies Corp. (United States)
Harry L. Graber, SUNY/Downstate Medical Ctr. (United States)
Randall Locke Barbour, SUNY/Downstate Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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