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Proceedings Paper

Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe
Author(s): Hanli Liu; Maureen Johns; Cole A. Giller
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Paper Abstract

Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500 - 590 nm) reflectance with source-detector separations of 0.125 - 0.25 mm and 0.25 - 1.0 mm. For the former case, the major modifications are D equals 1/3(mu) s, and z0 equals 1/(mu) s'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.

Paper Details

Date Published: 29 June 2001
PDF: 6 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434472
Show Author Affiliations
Hanli Liu, Univ. of Texas at Arlington and Univ. of Texas Southwestern Medical Ctr. at Dallas (United States)
Maureen Johns, Univ. of Texas at Arlington and Univ. of Texas Southwestern Medical Ctr. at Dallas (United States)
Cole A. Giller, Univ. of Texas Southwestern Medical Ctr. at Dallas (United States)


Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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