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Proceedings Paper

Imaging with dual-interfering sources
Author(s): Xavier Intes; Vasilis Ntziachristos; Arjun G. Yodh; Britton Chance
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Paper Abstract

Dual interfering source systems have been shown to be more sensitive to the presence of absorbing inhomogeneities than single-source systems. They are used to localize accurately deep inhomogeneities with backprojection methods. However, there is not actually a method to perform indirect imaging with such techniques. In this work, a tomographic reconstruction method for an absorbing perturbation in highly scattering media and for phased array system is derived. The perturbation approach to solve the heterogeneous diffusion equation is used with the first order Rytov expansion. Analytical weight functions necessary to solve the inverse problem are obtained. Validity of the derived analytical expressions was checked with reconstructions from simulated data obtained with finite difference solutions of the diffusion equation and for a media mimicking breast tissue.

Paper Details

Date Published: 29 June 2001
PDF: 8 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434471
Show Author Affiliations
Xavier Intes, Univ. of Pennsylvania (United States)
Vasilis Ntziachristos, Massachusetts General Hospital/Harvard Medical School (United States)
Arjun G. Yodh, Univ. of Pennsylvania (United States)
Britton Chance, Univ. of Pennsylvania (United States)

Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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