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Proceedings Paper

Optical monitoring of tissue viability using reflected spectroscopy in vivo
Author(s): Avraham Mayevsky; Ari Kraut; Tamar Manor; Judith Sonn; Yehuda Zurovsky
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Paper Abstract

Only few techniques that could provide real-time continuous multiparametric physiological data have been developed. Therefore, experimental and clinical monitoring devices for organ and tissue viability evaluation are still lacking. In this study, we present the new concept of tissue vitality defined as a product of a few parameters monitored in real- time by a combined measurement of tissue blood flow and volume as well as the oxidation reduction state of the mitochondria. The hypothesis behind the new approach is that in order to evaluate in real-time tissue vitality, it is necessary to monitor both microcirculatory blood flow and volume as well as the intracellular O2 balance as reflected in the mitochondrial redox state.

Paper Details

Date Published: 4 May 2001
PDF: 9 pages
Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); doi: 10.1117/12.431553
Show Author Affiliations
Avraham Mayevsky, Bar-Ilan Univ. (Israel)
Ari Kraut, Bar-Ilan Univ. (Israel)
Tamar Manor, Bar-Ilan Univ. (Israel)
Judith Sonn, Bar-Ilan Univ. (Israel)
Yehuda Zurovsky, Bar-Ilan Univ. (Israel)


Published in SPIE Proceedings Vol. 4241:
Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II
Valery V. Tuchin, Editor(s)

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