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Proceedings Paper

Diffuse and localized reflectance measurements of hemoglobin and hematocrit in human skin
Author(s): Omar S. Khalil; Xiaomao Wu; Shu-Jen Yeh; Tzyy-Wen Jeng
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Paper Abstract

We conducted visible/near infrared optical measurements on the forearm of human subjects using a commercial diffuse reflectance spectrophotometer, and a breadboard temperature- controlled localized reflectance tissue photometer. Calibration relationships were established between skin reflectance signal and reference blood hemoglobin (Hb) concentration, or hematocrit values (Hct). These were then used to predict Hb and Hct values from optical measurement in a cross validation analysis. Different linear least- squares models for the prediction of Hb and Hct are presented and shows the ability to predict both. It was possible to screen prospective blood donors with low Hb concentration. It was possible to predict anemic subjects in the limited prospective blood donor population.

Paper Details

Date Published: 4 May 2001
PDF: 7 pages
Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); doi: 10.1117/12.431522
Show Author Affiliations
Omar S. Khalil, Abbott Labs. (United States)
Xiaomao Wu, Abbott Labs. (United States)
Shu-Jen Yeh, Abbott Labs. (United States)
Tzyy-Wen Jeng, Abbott Labs. (United States)

Published in SPIE Proceedings Vol. 4241:
Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II
Valery V. Tuchin, Editor(s)

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