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Proceedings Paper

Improved detection of simulated thrombus by layer decomposition of coronary angiograms
Author(s): Robert A. Close; Craig A. Morioka; Craig K. Abbey; James Stuart Whiting
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Paper Abstract

Layer decomposition is a promising technique for background removal and noise reduction in coronary angiograms. Our layer decomposition algorithm decomposes a projection image sequence into multiple 2D layers undergoing translation, rotation, and scaling. We apply this layer decomposition algorithm to simulated angiograms containing stenotic vessels with and without thrombus. We constructed 85 pairs of simulated angiographic sequences by embedding each of 5 simulated vessels (with and without thrombus) in 17 clinical angiograms. We computed the response of a matched eye filter applied to (1) one raw image of each sequence at the time of minimal motion (RAW), (2) a layered digital subtraction angiography (LDSA) image of the same frame, and (3) the time-averaged vessel layer image (LAYER). We find that on average the LAYER and LDSA images have higher signal-to-noise ration and larger area under the receiver- operator characteristic curves (AUC) than the raw images.

Paper Details

Date Published: 3 July 2001
PDF: 7 pages
Proc. SPIE 4322, Medical Imaging 2001: Image Processing, (3 July 2001); doi: 10.1117/12.431150
Show Author Affiliations
Robert A. Close, Cedars-Sinai Medical Ctr. (United States)
Craig A. Morioka, Cedars-Sinai Medical Ctr. (United States)
Craig K. Abbey, Cedars-Sinai Medical Ctr. (United States)
James Stuart Whiting, Cedars-Sinai Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 4322:
Medical Imaging 2001: Image Processing
Milan Sonka; Kenneth M. Hanson, Editor(s)

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