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Proceedings Paper

Knowledge-based deformable surface model with application to segmentation of brain structures in MRI
Author(s): Amir Ghanei; Hamid Soltanian-Zadeh; Kost Elisevich; Jeffrey A. Fessler
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Paper Abstract

We have developed a knowledge-based deformable surface for segmentation of medical images. This work has been done in the context of segmentation of hippocampus from brain MRI, due to its challenge and clinical importance. The model has a polyhedral discrete structure and is initialized automatically by analyzing brain MRI sliced by slice, and finding few landmark features at each slice using an expert system. The expert system decides on the presence of the hippocampus and its general location in each slice. The landmarks found are connected together by a triangulation method, to generate a closed initial surface. The surface deforms under defined internal and external force terms thereafter, to generate an accurate and reproducible boundary for the hippocampus. The anterior and posterior (AP) limits of the hippocampus is estimated by automatic analysis of the location of brain stem, and some of the features extracted in the initialization process. These data are combined together with a priori knowledge using Bayes method to estimate a probability density function (pdf) for the length of the structure in sagittal direction. The hippocampus AP limits are found by optimizing this pdf. The model is tested on real clinical data and the results show very good model performance.

Paper Details

Date Published: 3 July 2001
PDF: 10 pages
Proc. SPIE 4322, Medical Imaging 2001: Image Processing, (3 July 2001); doi: 10.1117/12.431106
Show Author Affiliations
Amir Ghanei, Institute for Studies Henry Ford Health System and Univ. of Michigan (United States)
Hamid Soltanian-Zadeh, Henry Ford Health System, Univ. of Tehran, and Case Western Reserve Univ. (United States)
Kost Elisevich, Henry Ford Health System (United States)
Jeffrey A. Fessler, Univ. of Michigan (United States)


Published in SPIE Proceedings Vol. 4322:
Medical Imaging 2001: Image Processing
Milan Sonka; Kenneth M. Hanson, Editor(s)

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