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Proceedings Paper

3D image guidance in radiotherapy: a feasibility study
Author(s): Matthias Ebert; Burkhard A. Groh; Mike Partridge; Bernd M. Hesse; Thomas Bortfeld
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Paper Abstract

Currently, one major research field in radiotheraphy is focused on patient setup verification and on detection of organ motion and deformation. A phantom study is performed to demonstrate the feasibility of image guidance in radiotherapy. Patient setup errors are simulated with a humanoid phantom, which is imaged using a linear accelerator and a therapy simulator to address megavoltage and kilovoltage (kV) computed tomography (CT), respectively. Projections are recorded by a flat panel imager. The various data sets of the humanoid phantom are compared by mutual information matching. The CT investigations show that the spatial resolution is better than 1.6 mm for high contrast objects. The uncertainties remaining after mutual information matching are found to be less than 1 mm for translations and 1 degree(s) for rotations. The phantom study indicates that the detection of patient setup errors as well as organ motion or deformation is possible with a high accuracy, especially if a kV X-ray tube could be attached to the linear accelerator. The presented method allows sophisticated quality assurance of beam delivery in each fraction and may even enable the use of new concepts of adaptive radiotherapy.

Paper Details

Date Published: 3 July 2001
PDF: 10 pages
Proc. SPIE 4322, Medical Imaging 2001: Image Processing, (3 July 2001); doi: 10.1117/12.431070
Show Author Affiliations
Matthias Ebert, Deutsches Krebsforschungszentrum (Germany)
Burkhard A. Groh, Deutsches Krebsforschungszentrum (Germany)
Mike Partridge, Deutsches Krebsforschungszentrum (Germany)
Bernd M. Hesse, Deutsches Krebsforschungszentrum (Germany)
Thomas Bortfeld, Deutsches Krebsforschungszentrum (Germany)

Published in SPIE Proceedings Vol. 4322:
Medical Imaging 2001: Image Processing
Milan Sonka; Kenneth M. Hanson, Editor(s)

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