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Proceedings Paper

Flat-panel detector-based cone-beam volume CT breast imaging: preliminary phantom study
Author(s): Ruola Ning; Biao Chen; David L. Conover; Linda McHugh; Jeanne Cullinan; Rongfeng Yu
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Paper Abstract

The clinical goal of breast imaging is to detect tumor masses when they are as small as possible, preferably less than 10 mm in diameter. Conventional film-screen mammography is the most effective tool for the early detection of breast cancer currently available. However, conventional mammography has relatively low sensitivity to detect small breast cancers (under several millimeters). Specificity and the positive predictive value of mammography remain limited owing to an overlap in the appearance of benign and malignant lesions, and surrounding structure. The limitations accompanying conventional mammography is to be addressed by incorporating a cone beam volume CT reconstruction technique with a recently developed flat panel detector. A computer simulation study has been performed to prove the feasibility of developing a flat panel detector-based cone beam volume CT breast imaging (FPD-CBVCTBI) technique. In this study, a preliminary phantom experiment is conducted to verify the findings in the computer simulation using a prototype flat panel detector-based cone beam volume CT scanner. The results indicate that the FPD-CBVCTBI technique effectively removes structure overlap and significantly improves the detectability of small breast tumors. This suggests that FPD-CBVCTBI is a potentially powerful breast-imaging tool.

Paper Details

Date Published: 28 June 2001
PDF: 10 pages
Proc. SPIE 4320, Medical Imaging 2001: Physics of Medical Imaging, (28 June 2001); doi: 10.1117/12.430901
Show Author Affiliations
Ruola Ning, Univ. of Rochester Medical Ctr. (United States)
Biao Chen, Univ. of Rochester Medical Ctr. (United States)
David L. Conover, Univ. of Rochester Medical Ctr. (United States)
Linda McHugh, Univ. of Rochester Medical Ctr. (United States)
Jeanne Cullinan, Univ. of Rochester Medical Ctr. (United States)
Rongfeng Yu, Univ. of Rochester Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 4320:
Medical Imaging 2001: Physics of Medical Imaging
Larry E. Antonuk; Martin Joel Yaffe, Editor(s)

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