Share Email Print
cover

Proceedings Paper

Multiple-reader studies, digital mammography, computer-aided diagnosis, and the Holy Grail of imaging physics: I
Author(s): Robert F. Wagner; Sergey V. Beiden; Gregory Campbell
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

There are multiple sources of variability in clinical studies of imaging systems. The variation of the reader `mindset' establishes the need for ROC analysis to control for that fundamental variable. The demonstration of the range of reader skills in mammography shows the need for a multivariate approach to ROC analysis. The multiple-reader, multiple-case (MRMC) ROC experimental paradigm addresses this need and several practical solutions to the problem of analysis of MRMC data have been developed. We review the application of these methods to an important clinical comparison of digital and conventional mammography.

Paper Details

Date Published: 28 June 2001
PDF: 8 pages
Proc. SPIE 4320, Medical Imaging 2001: Physics of Medical Imaging, (28 June 2001); doi: 10.1117/12.430881
Show Author Affiliations
Robert F. Wagner, FDA Ctr. for Devices and Radiological Health (United States)
Sergey V. Beiden, FDA Ctr. for Devices and Radiological Health (United States)
Gregory Campbell, FDA Ctr. for Devices and Radiological Health (United States)


Published in SPIE Proceedings Vol. 4320:
Medical Imaging 2001: Physics of Medical Imaging
Larry E. Antonuk; Martin Joel Yaffe, Editor(s)

© SPIE. Terms of Use
Back to Top