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Proceedings Paper

Spectral features of spatially coherent light backscattered from cartilage
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Paper Abstract

During laser irradiation, mechanically deformed cartilage undergoes a temperature dependent phase transformation resulting in accelerated stress relaxation. Clinically, laser-assisted cartilage reshaping may be used to recreate the underlying cartilaginous framework in structures such as ear, larynx, trachea, and nose. Therefore, research and identification of the biophysical transformations in cartilage accompanying laser heating are valuable to develop many potential clinical applications. To observe spectral features in quasi-elastic light scattering from cartilage, light emitted from a Nd:YAG laser (? = 1.32?m) was used for a heating source and a Ti:Al2O3 femtosecond laser (? = 850nm) was used for a light scattering source. A spectrometer and infrared detector were used to monitor the backscattered light spectrum and transient temperature changes from cartilage following laser irradiation. A cartilage sample was irradiated by Nd:YAG laser light over a 6 second time period and the transient temperature was simultaneously measured during laser irradiation. The denaturation of macromolecules within cartilage was observed after 4.5 seconds. The obtained spectral data were analyzed by computing a Fast Fourier transform and converted to the optical path length difference domain. The path length difference of a spectral oscillation within cartilaginous framework was also calculated. Although the measured path length differences were different from the expected values, the results will give rise to distinct patterns of the movement of macromolecules within cartilage following laser irradiation.

Paper Details

Date Published: 17 June 2002
PDF: 5 pages
Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); doi: 10.1117/12.430684

Published in SPIE Proceedings Vol. 4609:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII
Lawrence S. Bass; Abraham Katzir; Eugene A. Trowers; Timothy A. Woodward; Werner T.W. de Riese; Kenneth Eugene Bartels; Lloyd P. Tate; George M. Peavy; Michael D. Lucroy; Lawrence S. Bass; Nikiforos Kollias; Kenton W. Gregory; Udayan K. Shah; Brian Jet-Fei Wong; David S. Robinson; Hans-Dieter Reidenbach; Kenneth Eugene Bartels; Lawrence S. Bass; Werner T.W. de Riese; Kenton W. Gregory; Abraham Katzir; Nikiforos Kollias; Michael D. Lucroy; Reza S. Malek; George M. Peavy; Hans-Dieter Reidenbach; David S. Robinson; Udayan K. Shah; Lloyd P. Tate; Eugene A. Trowers; Brian Jet-Fei Wong; Timothy A. Woodward, Editor(s)

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