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Proceedings Paper

Surface-enhanced infrared absorption of nucleic acids on gold substrate in FTIR reflectance mode
Author(s): G. I. Dovbeshko; Vladimir I. Chegel; Nina Y. Gridina; O. P. Repnytska; I. V. Sekirin; Yuri M. Shirshov
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Paper Abstract

Data on surface enhanced infrared absorption (SEIRA) of nucleic acids deposited on the metal surface have been obtained in the experiment in FTIR reflectance mode. As metal surface, we used Au of 200 - 500 Angstrom thickness on quartz substrate. Roughness of Au was not greater than 50 Angstrom. In our experimental conditions, the enhancement factor of SEIRA was about 3 - 7. We obtained different enhancement factors for different vibrations of nuclei acids. Application of this method to the tumour brain nucleic acid gave a possibility to reveal some structural peculiarities of their sugar-phosphate backbone.

Paper Details

Date Published: 12 June 2001
PDF: 5 pages
Proc. SPIE 4425, Selected Papers from the International Conference on Optoelectronic Information Technologies, (12 June 2001); doi: 10.1117/12.429717
Show Author Affiliations
G. I. Dovbeshko, Institute of Physics (Ukraine)
Vladimir I. Chegel, Institute of Semiconductor Physics (Ukraine)
Nina Y. Gridina, A.P. Romodanov Institute of Neurosurgery (Ukraine)
O. P. Repnytska, Institute of Physics (Ukraine)
I. V. Sekirin, Institute of Physics (Ukraine)
Yuri M. Shirshov, Institute of Semiconductor Physics (Ukraine)

Published in SPIE Proceedings Vol. 4425:
Selected Papers from the International Conference on Optoelectronic Information Technologies
Sergey V. Svechnikov; Volodymyr P. Kojemiako; Sergey A. Kostyukevych, Editor(s)

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