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Proceedings Paper

Optical diagnostics of toxic heavy metal ion's effect on plasma blood proteins
Author(s): Galina P. Petrova; Yurii M. Petrusevich; Anastasya N. Evseevicheva; Dmitrii I. Ten
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Paper Abstract

For the first time, the formation of macromolecular protein clusters in water solutions in the presence of heavy metal ions were observed by the light scattering method. Conditions of the formation and destruction of such clusters were investigated. The clusters mass has a maximum value at the isoelectric point of the protein and increases with the ionic strength of the solution. Formation of clusters in the presence of toxic heavy metals in the blood and living cells is believed to have an essential physiological meaning. The molecular mechanisms of clusters formation based on dipole- dipole interactions of the macromolecules are discussed.

Paper Details

Date Published: 13 June 2001
PDF: 11 pages
Proc. SPIE 4263, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring, (13 June 2001); doi: 10.1117/12.429334
Show Author Affiliations
Galina P. Petrova, M.V. Lomonosov Moscow State Univ. (Russia)
Yurii M. Petrusevich, M.V. Lomonosov Moscow State Univ. (Russia)
Anastasya N. Evseevicheva, M.V. Lomonosov Moscow State Univ. (Russia)
Dmitrii I. Ten, M.V. Lomonosov Moscow State Univ. (Russia)


Published in SPIE Proceedings Vol. 4263:
Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring
Alexander V. Priezzhev; Gerard L. Cote, Editor(s)

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