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Proceedings Paper

Optoacoustic supercontrast for early cancer detection
Author(s): Alexander A. Karabutov; Elena V. Savateeva; Alexander A. Oraevsky
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Paper Abstract

Thermal mechanism is fundamental for the generation of ultrasonic waves in a course of absorption of laser radiation. Its efficiency is relatively low, but increases significantly with temperature (thermal non-linearity). If the phase transition of the irradiated medium occur, the efficiency may exceed its linear regime value several orders of magnitude. The idea of optoacoustic supercontrast for early cancer detection is based on this fact. We performed feasibility studies and describe requirements to and properties of the optoacoustic supercontrast agent based on nanoscopid particles. The results of the preliminary experiments with the metal and carbon nanoparticles as optoacoustic generation up to three orders of magnitude under irradiation conditions of laser optoacoustic imaging in the depth of human tissue.

Paper Details

Date Published: 15 June 2001
PDF: 9 pages
Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); doi: 10.1117/12.429306
Show Author Affiliations
Alexander A. Karabutov, Univ. of Texas Medical Branch at Galveston (United States)
Elena V. Savateeva, Univ. of Texas Medical Branch at Galveston (United States)
Alexander A. Oraevsky, Univ. of Texas Medical Branch at Galveston (United States)


Published in SPIE Proceedings Vol. 4256:
Biomedical Optoacoustics II
Alexander A. Oraevsky, Editor(s)

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