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Proceedings Paper

Transient grating of laser-induced 1ΔgO2 production by photodynamic therapy agents
Author(s): Andrew C. Beveridge; Barbara A. Bench; Irio G. Calasso; Sergiu M. Gorun; Gerald J. Diebold
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Paper Abstract

The transient grating method acts as a monitor of the evolution of thermal energy following optical excitation of an absorbing molecule. The signals produced by a photodynamic therapy agent are shown to be strongly dependent on presence of oxygen in solution indicating transfer of energy from a triplet state of the dye to form excited 1Δg oxygen. Analysis of the data shows that the efficiency of excited oxygen production can be determined by a recording of the diffracted light intensity versus time.

Paper Details

Date Published: 15 June 2001
PDF: 5 pages
Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); doi: 10.1117/12.429304
Show Author Affiliations
Andrew C. Beveridge, Brown Univ. (United States)
Barbara A. Bench, Brown Univ. (United States)
Irio G. Calasso, Brown Univ. (United States)
Sergiu M. Gorun, Brown Univ. (United States)
Gerald J. Diebold, Brown Univ. (United States)


Published in SPIE Proceedings Vol. 4256:
Biomedical Optoacoustics II
Alexander A. Oraevsky, Editor(s)

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