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Proceedings Paper

Performance of amplitude-modified second-order Gaussian filter for the detection of retinal blood vessel
Author(s): Gang Luo; Opas Chutatape; Sanjay M. Krishnan
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Paper Abstract

Automated analysis of vessel morphology is valuable in diagnosis since it can provide measurable abnormalities in diameter and tortuosity that reflect systemic or local ocular disease. Although the center point of vessel can be easily detected with matched filter, the diameter cannot be obtained from the readily available convolution result in the process of location detection. An amplitude modified second-order Gaussian filter is presented in this paper. Simulation shows that a profile of vessel matches only one amplitude modified second-order Gaussian filter, with which the convolution peak reaches its maximum. Therefore, the width specified parameter of vessel model can be figured out by matching operation with a group of modified Gaussian filters. A vessel diameter measurement concept based on calibration is presented in order to avoid the burden of finding the exact edges of vessels, which has caused several different width definitions for the endless Gaussian curve. The real vessel width can be determined simply according to the relationship built through a calibration procedure in advance after the width specified parameter of Gaussian curve is obtained. Experiments of blood vessel detection of color fundus image are given. The results of the vessel diameter measurement show good agreement with visual inspection.

Paper Details

Date Published: 7 June 2001
PDF: 10 pages
Proc. SPIE 4245, Ophthalmic Technologies XI, (7 June 2001); doi: 10.1117/12.429267
Show Author Affiliations
Gang Luo, Nanyang Technological Univ. (Singapore)
Opas Chutatape, Nanyang Technological Univ. (Singapore)
Sanjay M. Krishnan, Nanyang Technological Univ. (Singapore)

Published in SPIE Proceedings Vol. 4245:
Ophthalmic Technologies XI
Fabrice Manns; Per G. Soederberg; Arthur Ho, Editor(s)

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