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Proceedings Paper

Interpretation of arterial velocity waveforms
Author(s): Peter J. Yim; Juan Raul Cebral; Rainald Loehner; Orlando Soto; Hani Marcos; Peter L. Choyke
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Paper Abstract

Blood flow temporal waveforms change with position along an artery. The change in the flow waveforms can be accounted for by a transmission line model of flow. According to this model, pulse waves propagate at a finite velocity in both directions along the artery. In principle, given flow waveforms measured at three locations along an artery, the pulse-wave velocity, (c) can be determined from the wave equation (d2Q/dt2 equals c2d2Q/dz2, Q is flow, t is time, z is position). Given the vessel diameter, the vessel-wall compliance can be derived from pulse-wave velocity. However, direct solution of the wave equation for pulse-wave velocity is highly susceptible to flow-measurement error. Thus, we propose a new method for estimating pulse-wave velocity from arterial flow waveforms. In our method, ideal flow waveforms are reconstructed from three measured flow waveforms. The ideal waveforms are reconstructed by minimization of the total error between the ideal and measured waveforms subject to constraints of the wave equation. Ideal flow waveforms are reconstructed for a range of assumed pulse-wave velocities. The true pulse-wave velocity is considered to be that which produces the minimum total error. The method applied to blood flow measurements made with phase-contrast magnetic resonance imaging.

Paper Details

Date Published: 21 May 2001
PDF: 11 pages
Proc. SPIE 4321, Medical Imaging 2001: Physiology and Function from Multidimensional Images, (21 May 2001); doi: 10.1117/12.428123
Show Author Affiliations
Peter J. Yim, National Institutes of Health (United States)
Juan Raul Cebral, George Mason Univ. (United States)
Rainald Loehner, George Mason Univ. (United States)
Orlando Soto, George Mason Univ. (United States)
Hani Marcos, National Institutes of Health (United States)
Peter L. Choyke, National Institutes of Health (United States)

Published in SPIE Proceedings Vol. 4321:
Medical Imaging 2001: Physiology and Function from Multidimensional Images
Chin-Tu Chen; Anne V. Clough, Editor(s)

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