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Proceedings Paper

Robust registration method for interventional MRI-guided thermal ablation of prostate cancer
Author(s): Baowei Fei; Andrew Wheaton; Zhenghong Lee; Kenichi Nagano; Jeffrey L. Duerk; David L. Wilson
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Paper Abstract

We are investigating methods to register live-time interventional magnetic resonance imaging (iMRI) slice images with a previously obtained, high resolution MRI image volume. The immediate application is for iMRI-guided treatments of prostate cancer. We created and evaluated a slice-to-volume mutual information registration algorithm for MR images with special features to improve robustness. Features included a multi-resolution approach and automatic restarting to avoid local minima. We acquired 3D volume images from a 1.5 T MRI system and simulated iMRI images. To assess the quality of registration, we calculated 3D displacement on a voxel-by-voxel basis over a volume of interest between slice-to-volume registration and volume-to- volume registrations that were previously shown to be quite accurate. More than 500 registration experiments were performed on MR images of volunteers. The slice-to-volume registration algorithm was very robust for transverse images covering the prostate. A 100% success rate was achieved with an acceptance criterion of <1.0 mm displacement error over the prostate. Our automatic slice-to-volume mutual information registration algorithm is robust and probably sufficiently accurate to aid in the application of iMRI- guided thermal ablation of prostate cancer.

Paper Details

Date Published: 28 May 2001
PDF: 8 pages
Proc. SPIE 4319, Medical Imaging 2001: Visualization, Display, and Image-Guided Procedures, (28 May 2001); doi: 10.1117/12.428092
Show Author Affiliations
Baowei Fei, Case Western Reserve Univ. (United States)
Andrew Wheaton, Case Western Reserve Univ. (United States)
Zhenghong Lee, Univ. Hospitals of Cleveland (United States)
Kenichi Nagano, Case Western Reserve Univ. (United States)
Jeffrey L. Duerk, Univ. Hospitals of Cleveland and Case Western Reserve Univ. (United States)
David L. Wilson, Case Western Reserve Univ. and Univ. Hospitals of Cleveland (United States)


Published in SPIE Proceedings Vol. 4319:
Medical Imaging 2001: Visualization, Display, and Image-Guided Procedures
Seong Ki Mun, Editor(s)

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