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Proceedings Paper

Culture of bone-marrow-derived cells in microfabricated pit arrays
Author(s): Hiroko E. Kikuchi; Yuji Kikuchi; Yoshinori Kuboki
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Paper Abstract

Tissue cells cannot survive without the attachment to extracellular matrix (ECM). Furthermore, the geometry of ECM is known to play an essential role in the regulation for these cells to proliferate and differentiate so that tissues with normal morphologies can be formed or maintained. We have introduced microfabricated surface structures coated with ECM protein collagen into cell culture studies to examine a possibility of 3D patterning of ECM.

Paper Details

Date Published: 21 May 2001
PDF: 10 pages
Proc. SPIE 4265, Biomedical Instrumentation Based on Micro- and Nanotechnology, (21 May 2001); doi: 10.1117/12.427973
Show Author Affiliations
Hiroko E. Kikuchi, Hokkaido Univ. (Japan)
Yuji Kikuchi, National Food Research Institute (Japan)
Yoshinori Kuboki, Hokkaido Univ. (Japan)


Published in SPIE Proceedings Vol. 4265:
Biomedical Instrumentation Based on Micro- and Nanotechnology
Raymond P. Mariella; Dan V. Nicolau, Editor(s)

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